Assessment of Efficacy and Safety of Ivermectin in the Patients of COVID-19
AbstractObjective: Primary objective of the study is to evaluate the efficacy and safety of ivermectin in reducing the progression and severity of Covid-19. Secondary objective of the study is to compare viral clearance rate among the study group and evaluation of side effects of therapy.
MethodsThis cross-sectional observational study was undertaken at Department of Pulmonology Fatima Memorial Hospital, Lahore.After taking a medical history and doing a physical examination, oral ivermectin(12 mg once daily for 5 days) was given to 350 patients with COVID-19. Throughout treatment, the clinical efficacy of ivermectin, viral clearance rate, and adverse effects of medication were assessed and recorded on a prepared Performa.
Results Ivermectin therapy demonstrated 99.9 percent efficacy in patients treated with it. The paired sample t test revealed statistically significant differences in radiographic findings and PCR laboratory examination prior to and following ivermectin administration. While all clinical symptoms improved following medication. On the other hand, 2 persons (4%) have reported experiencing adverse effects from the medicine.
Conclusion Ivermectin induction has been presented as a more successful technique for treating Covid-19 infection
Keywords:Ivermectin, Covid-19, anti-helmenthic
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