Correlation of Severity of Esophageal Varices with Platelet Count in Patients Of Chronic Liver Disease


  • Author- Nazish Shafi, Hafiz Abdul Rauf, Fahad Aman Khan, Muhammad Imran, Imran Khan, Wafa Qaisar


Objective: The objective of this study was to ascertain if the platelet count of individuals with decompensated CLD and the grading of their esophageal varices were correlated.


This study used non-probability purposive sampling to undertake a descriptive cross-sectional analysis. There were 150 individuals with decompensated liver cirrhosis in all. Each patient received an endoscopy to grade their esophageal varices, and a platelet count was performed on each one. The spearman's rank-C correlation approach was utilized to establish correlation.


 38.3% of patients with platelets count < 50,000/mm3 and 61.7% of patients with third grade esophageal varices were found in this group of patients. Of the patients whose platelet counts ranged from 51,000 to 99,000/mm3, 28.1% had second-grade esophageal varices, and 40.6% had third-grade varices. In patients with a platelet count between 100,000 and 149,00/mm3, second- and third-grade esophageal varices affected 17.9% and 23.1% of patients, respectively. With a p-value of less than 0.001, the Spearman's rank correlation test showed a negative relationship between platelet count and esophageal varices' grading.


 This research shows a statistically significant negative correlation between the grading of esophageal varices and platelet count. As a result, in scenarios when endoscopic resources are unavailable, the platelet count could serve as a predictor of esophageal varices.


Chronic liver disease, WHO Esophageal varices