Transmissible Infection Profile and Hematological Parameters in Healthy Blood Donors and Trends in Unsuitability for Blood Donation

Authors

Abstract

Objective: This study assessed the prevalence of HIV, syphilis, dengue, malaria, HBV, HCV, and other transfusiontransmitted infections (TTIs) among healthy blood donors in Rawalpindi, Pakistan.

Methods

This study examined blood donors who visited the Al-khidmat Raazi Diagnostic and Blood Bank between January and September of 2022. Blood donors underwent tests for dengue, malaria, syphilis, HIV, HBV, and HCV. To separate serum from blood, 5 ml of blood is collected in a sterile test tube and centrifuged at 3500 rpm for 5 minutes. Using ICT, screening was done for HbsAg, anti-HCV, anti-syphilis, and anti-HIV antibodies.

Results

 Ninety percent of the blood donors had typical physical characteristics. Male donors made up all 298 (100%) of the healthy donors. Over the course of nine months, TTIs were tested for in 298 healthy blood donors. In our study, replacement donors made up 80% of the blood donors. The prevalence of malaria, dengue, HBV, HCV, HIV, syphilis, and other diseases was determined to be 12.5%, 13.4%, 12.8%, 6.7%, 0.7%, and 21.5% respectively. The hemoglobin level of 260 blood donors (87%) was 13mg/dl

Conclusion

 Donors frequently experience TTIs. Inadequate screening leads to transfusion-transmissible illnesses in healthy blood donors. Safe health practices and appropriate TTI screening could lower blood donors' risk of contracting communicable illnesses. To avoid unintentional transfusion reactions in both the recipient and the donor, the hospital must thoroughly screen donors for TTIs and unfitness

Keywords:

TTIs infection, HBV, Blood donor, Syphilis, Malaria, HBV, Dengue, HIV

Published

2024/08/30

Issue

Vol. VOLUME 5-Issue 3
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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