Frequency of Renal Impairment Among Patients with Liver Cirrhosis with Spontaneous Bacterial Peritonitis

Authors

Abstract

Objective: This study aim was to ascertain the prevalence of renal impairment among patients diagnosed with spontaneous bacterial peritonitis resulting from liver cirrhosis.

Methods

The descriptive cross-sectional study was conducted in the Department of Gastroenterology, Hayatabad Medical Complex, located in Peshawar. The study duration was 6 months from September 29th, 2022 to March 29th, 2022. A cohort of 212 individuals was examined to ascertain the prevalence of renal dysfunction among patients afflicted with spontaneous bacterial peritonitis because of liver cirrhosis.

Results

 A total of 212 patients were recruited in which 34.3% (n=72 ) were found in aged 31-40 years. The mean age of the participants was 51.5±3.3 years. Among total, 87 (41.4%) were male and 123 (58.6%) were female patients. Among total, 48 (22.9%) were found in underweight range. It was observed that 96 patients (45.7%) had renal impairment, while 114 patients (54.3%) not affected with renal impairment. The analysis revealed that smoking was seen in 80 individuals (38.1%), whereas hypertension was observed in 120 individuals (57.1%).

Conclusion

 Renal impairment has significant prevalent occurrence among cirrhotic patients presenting with ascites and spontaneous bacterial peritonitis (SBP). The SBP-RI variable has significant predictive value for hospital mortality in individuals diagnosed with SBP. Individuals who have significantly compromised liver function or pre-existing kidney failure are more susceptible to the development of spontaneous bacterial peritonitis with renal impairment.

Keywords:

Renal impairment, Spontaneous bacterial peritonitis, Liver cirrhosis

Published

2024/08/30

Issue

Vol. VOLUME 5-Issue 3
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