Pediatric Acute Lymphoblastic Leukemia in Rawalpindi
Abstract
Objective: To identify the incidences of ALL, it's Diagnostic, clinical and its prognostic aspect from CMH Rawalpindi hospital PakistanMethods
Diagnosis and screening forALLwas done at CMH Rawalpindi from 2010-2021. During this time, 981 individuals under the age of 19 who had recently been diagnosed with acute lymphoblastic leukemia. Cytological, immunophenotypic, and cytogenetic criteria were employed to diagnose. Chi-square and Fisher's exact tests assessed prognostic factor associations.Results
The collected data from 2010-2021, showed that Males predominated the incidence rate 626 (63.8%), average diagnostic age was 6.3-0.5 years. Results showed that 207(21.10%) were children less than 3 years old, 587(59.80%) were between 3-10 years old. While 187(19%) were above age of 10. After statistical analysis, patients at standard risk were found to be (496)50.5% while 485(49.5%) were at high risk. The collected data reported prevalence ofALLin (850)86.6% patients while 131(13.3%) patients were diagnosed with Albl. The survival rate of patients having disease and that of survival rate with disease free conditions was found in 655(66.7%) and 326(33.3%) patients respectively. Patients with normal nutritional status 726(74%), with moderate eating 165(16.80%) and eating severely 90(9.2%) was reported and analyzed.Conclusion
ALL is found to be one of threat in young children and adolescence. There is a threat of relapse even after recovery from ALL when treated specifically in adolescence. Early prognosis and diagnosis of ALL is necessary to mitigate its effects and to avoid its recurrence. Health authorities in this regard should provide the required facilities to overcome this menace.Keywords:
Acute Lymphoblastic Leukemia, Malignancy, T-ALL, Standard risk, High risk.Published
2024/08/30
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