Kikuchi-Fujimoto Disease with Subsequent Meningoencephalitis Insights into Rare Complications – A Case Report

Authors

Abstract

Kikuchi-Fujimoto Disease (KFD) is a rare, benign, self-limiting condition primarily affecting young adults and is often misdiagnosed due to its nonspecific symptoms. We present a rare case of a 36-year-old man who presented with highgrade fever, cervical lymphadenopathy, and weight loss. Despite a comprehensive workup, involving imaging studies and laboratory investigations, the diagnosis remained elusive until a lymph node excisional biopsy confirmed the Kikuchi disease. The patient developed meningoencephalitis, a rare but severe complication of KFD, characterized by seizures and altered mental status.Supportive care including non-steroidal anti-inflammatory drugs, and corticosteroids are the mainstay of management. The patient was discharged with a good prognosis. This case highlights the diagnostic challenges and potential severe neurological complications of KFD, emphasizing the need for heightened awareness and vigilant follow-up.

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Published

2024/08/30