Comparison of Left Ventricular Mass Index and Prolonged QTInterval in Type 2 Diabetic Patients

Authors

Abstract

Objective: To compare left ventricular mass index and QT interval in type 2 diabetic and non-diabetic patients.

Methods

108 patients with 54 in each group were inducted. Group A (case) were diabetic type 2 and group B (control) were non-diabetic. The study was conducted in the medicine department of Lahore General hospital.

Results

 In this study, the mean age in diabetic and non-diabetic subjects was 47.54 ± 9.25 and 44.53 ± 10.53 respectively with no significant difference, p-value = 0.199. In the diabetic group, there were 29 (53.70%) males and 25 (46.30%) females while in the non-diabetic group there were 27 (50%) male and 27 (50%) female patients. The mean LVMI in diabetic patients was significantly higher (129.48±30.72) as compared to control (49.30) with p-value<0.001. The mean QT in diabetic and non-diabetic was 431.65ms and 387.33ms while corrected QT interval was 468.31ms and 413.37ms respectively.

Conclusion

 The results of this study suggest that both LVMI and QT interval are higher in diabetic population when compared to non-diabetic subjects. Early screening and proper diagnosis must be adopted in type 2 diabetic patients as they are very prone to develop higher left ventricular mass and deranged QT interval can further lead to significant cardiovascular risk because left ventricular hypertrophy and deranged QT interval are absolute risk factors for ventricular arrhythmia, infarction of myocardium, coronary artery disease, cardiac failure and sudden mortality.

Keywords:

Congestive heart failure, hypertension and diabetes

Published

2024/12/09