Pulmonary Function Test Abnormalities in Patients of Chronic Kidney Disease at a Tertiary Care Hospital of Lahore
Abstract
Objective: To evaluate the pulmonary function test abnormalities in patients of chronic kidney disease (CKD).Methods
This prospective study was conducted at the Department of Pulmonology and Critical Care, Central Park Teaching Hospital, Lahore, from June 2023 to December 2023. A total of 61 patients were enrolled after getting an informed consent. Spirometry pulmonary function tests were done for all enrolled patients before and after hemodialysis.Results
Out of the total 61 patients, there were 28 male (45.9%) and 33 (54.1%) female participants with a mean age of 45.40±8.45 years. The mean FVC% of the enrolled patients before hemodialysis was 47.8 ± 27.9% and after hemodialysis was 58.2±5.2% with a statistically significant P-value. The mean FEV1% of the enrolled patients before hemodialysis was 40.24±2.37% and after hemodialysis was 48.2±4.2% with a statistically significant P-value. The mean FEV1/FVC (%) of the enrolled patients before hemodialysis was 68.0±2.70% and after hemodialysis was 81.9±1.9% with a statistically significant P-value. The mean FEF 25-75% of the enrolled patients before hemodialysis was 53.34±2.46% and after hemodialysis was 57.8±2.1% with a statistically significant P-value. The mean PEF% of the enrolled patients before hemodialysis was 46.8±3.3% and after hemodialysis was 51.7±2.7% with a statistically significant P-value.Conclusion
We concluded that there were significant improvements in pre- and post-hemodialysis spirometry parameters. Therefore, this study will help the clinical practitioner to consider treatment strategies keeping in mind the comorbidities in CKD patients.Keywords:
Pulmonary function abnormalities, CKD, Hemodialysis, BMI, Forced vital capacity, Peak expiratory flow rate.Published
2025/06/05
Issue
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