Original Research

Neonatal Sepsis: Accuracy of Hematological Scoring System for Diagnosing Neonatal Sepsis

Fareeha Abbas1
Mayo Hospital, Lahore
Bushra Ahmad1
Mayo Hospital, Lahore
Sadia Shabir1
Mayo Hospital, Lahore
Khawaja Amjad Hassan2
Services Hospital, Lahore

✉ Correspondence: Sadia Shabir Email: drsadiashabir@gmail.com

DOI https://doi.org/10.70302/jpsim.v4i1.2310
Volume: 4, Issue 1 Pages: 46–50 Published: 13 Feb 2023
Received: 11 Nov 2022 Accepted: 16 Dec 2022 Published Online: 13 Feb 2023

Abstract

Objective

To find the diagnostic accuracy of hematological scoring system in early diagnosis of neonatal sepsis taking blood culture as gold standard.

Methods

After IRB approval, this Cross sectional study was done in the Department of Pediatric Medicine, Mayo Hospital/ KEMU Lahore, for 6 months (Apr-Oct 2018). After informed parental consent, information including age, sex and anthropometric data were recorded. The laboratory investigations were sent to laboratory of Mayo Hospital. Complete blood counts including TLC and platelets count were done using Sysmax method. Neonatal sepsis was labeled as positive or negative on hematological score system and blood cultures.

Results

The mean age of neonates was 14.20 ± 8.09 days. There were 60(60%) male and 40(40%) female babies. Mean weight and length of these babies were 3.05 ± 0.46 kg and 51.49 ± 1.41 cm. A total of 41(41%) babies had neonatal sepsis on hematological score and 38(38%) on blood culture. The Sensitivity, Specificity, Positive Predictive Value, Negative Predictive Value and Diagnostic Accuracy was 81.58%, 85.48%, 77.50%, 88.33% and 84.00% respectively.

Conclusion

Hematological scoring system has high diagnostic accuracy in diagnosing neonatal sepsis at earliest, taking blood culture as gold standard.

Keywords
Diagnostic accuracy Hematological scoring sepsis

How to Cite This Article

Abbas F, Ahmad B, Shabir S, Hassan KA. Neonatal Sepsis: Accuracy of Hematological Scoring System for Diagnosing Neonatal Sepsis. J Pak Soc Intern Med. 2023;4(1):46–50. doi:10.70302/jpsim.v4i1.2310

Conflict of Interest

All authors declare no competing interests.

Disclosed in accordance with ICMJE and COPE guidelines.

Funding

No specific funding was received for this research.

Funder information follows the Crossref Funder Registry standard.

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Reference list indexed for Google Scholar and ResearchGate. DOI links resolve via doi.org.

CC BY CC BY 4.0 This article is published under the Creative Commons Attribution 4.0 International License. May be shared and adapted with attribution. © 2023 Journal of Pakistan Society of Internal Medicine.
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